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Watchmaker Genomics

Americas

Boulder

,

United States

Scaleup

FOUNDED

2019

HEADCOUNT

101-500

FUNDING

Series A

Keywords:

enzymes, directed_evolution, AI/ML, HTP_screening, omics

BUSINESS

Watchmaker Genomics uses directed evolution and computational protein engineering to develop high-performance enzymes and reagent kits for next-generation sequencing, molecular diagnostics, and synthetic biology applications. Products include DNA and RNA library preparation kits, engineered reverse transcriptases (StellarScript), polymerases, and methylation sequencing technologies (TAPS+). The company has enzyme manufacturing operations in both Boulder and South Africa (inherited from the Kapa Biosystems team's origins in Cape Town).

BIOTECH INVOLVEMENT

Watchmaker is a protein engineering and enzyme manufacturing company. The core platform uses directed evolution, computational biology, and high-throughput screening to engineer enzymes with enhanced performance characteristics (thermostability, inhibitor tolerance, fidelity, processivity).

TECHNOLOGY PLATFORM

computational biology; protein engineering; enzyme optimization

PRIMARY PRODUCTS

DNA/RNA library prep kits; RPA enzymes; NGS amplification solutions

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