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Prolific Machines

Americas

Emeryville

,

United States

Startup

FOUNDED

2020

HEADCOUNT

21-100

FUNDING

Series B

Keywords:

mammalian_cells, AI/ML, bioreactor_design, antibodies, vaccines

BUSINESS

Prolific Machines is developing an optogenetics-based biomanufacturing platform that uses light to control gene expression in production bioreactors. The Photomolecular platform integrates optogenetic cell line engineering, proprietary illumination hardware, and AI-driven bioprocess optimization. Achieved 200-liter optogenetic bioproduction in stainless steel (April 2025). Current focus is mammalian cell applications (antibodies, vaccines, nutritional proteins).

BIOTECH INVOLVEMENT

Core optogenetic biotechnology platform for enhanced bioprocess control.

TECHNOLOGY PLATFORM

optogenetics; AI bioprocess optimization

PRIMARY PRODUCTS

Optogenetic cell lines; illumination systems for bioreactors

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