Profluent
Americas
Emeryville
,
United States
Startup
FOUNDED
2022
HEADCOUNT
21-100
FUNDING
Series B
Keywords:
AI/ML, gene_editing, enzymes, therapeutics
BUSINESS
Profluent, founded in 2022 and based in Emeryville, California, uses large generative AI models to design novel functional proteins from scratch. The company's ProGen3 model (46B parameters, trained on 3.4B protein sequences) was the first to demonstrate scaling laws for protein design. OpenCRISPR-1, the first fully AI-designed CRISPR system, published in Nature (2025). Protein Atlas of 115B+ sequences.
BIOTECH INVOLVEMENT
Core AI-driven protein engineering platform for biotechnology discovery and development.
TECHNOLOGY PLATFORM
generative AI; protein design; CRISPR engineering
PRIMARY PRODUCTS
OpenCRISPR gene editor; AI-designed proteins