top of page

Primrose Bio

Americas

San Diego

,

United States

Established

FOUNDED

2023

HEADCOUNT

21-100

FUNDING

Growth / PE-backed

Keywords:

fermentation, precision_fermentation, bacteria, therapeutics, vaccines, CDMO, enzymes

BUSINESS

Primrose Bio is a protein expression and enzyme engineering company formed through the merger of Pelican Technology Holdings (formerly Pfenex, a Ligand Pharmaceuticals subsidiary) and Primordial Genetics. The company holds more than 200 patents globally and operates two core platforms: Pelican Expression Technology, a Pseudomonas fluorescens-based recombinant protein production system used in six approved products, and Function Generator, an ultra-high-throughput novel gene generation system for enzyme and microbe discovery.

BIOTECH INVOLVEMENT

Recombinant protein expression and enzyme engineering are the entire basis of the business, anchored on a P. fluorescens microbial host platform for therapeutic and vaccine protein manufacturing. The Function Generator platform supports gene library generation and enzyme discovery, and the Prima RNApols product line targets the mRNA manufacturing supply chain.

TECHNOLOGY PLATFORM

Pfenex Expression Technology (Pseudomonas fluorescens); Prima RNApols

PRIMARY PRODUCTS

Pfenex platform for antibody derivatives and vaccine antigens; Prima RNApols for mRNA; PeliCRM197 carrier protein

© 2026 Apex Bio Consulting. All rights reserved.

bottom of page